CDS: SPCC70.03c


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General Information

Systematic Name

SPCC70.03c

Status

role inferred from homology

Product

proline dehydrogenase (predicted)

Type

CDS

Sequence

DNA and Protein

Location

Chromosome

Contig Location

complement(2350728..2352206) (Unspliced length: 1479 bp)

Exons

complement(2350728..2352206) (Spliced length: 1479 bp)

Region download and display (in Artemis)

Genome Browser

Context Map:
Context Feature Map

SPCC1494.07 SPCC1494.08c SPCC1494.09c adn3 SPCC70.02c >SPCC70.03c< SPCC70.04c ecl1 SPCC70.05c SPNCRNA.519 SPNCRNA.520

Curation

Term	Other genes annotated to this term
orthologous to S. cerevisiae YLR142W	(0 Others)
conserved in Eukaryotes	(4113 Others)
conserved in Bacteria	(830 Others)
conserved in Metazoa	(3558 Others)
conserved in Vertebrates	(3556 Others)
conserved in Fungi	(4163 Others)
predominantly uniformly single copy (one to one)	(2867 Others)

Predicted Peptide Properties

Mass

55.8 kDa	Amino acids	492
pH 8.9	Charge	17.0

Isoelectric point

Signal Peptide

Not found

Transmembrane Domains

0 found

GPI Anchor

Not found

Gene Ontology Annotation

Term (browse Amigo)	Evidence	Other genes annotated to this term
Biological Process
glutamate biosynthetic process	ISS (PMID:17072883) with UniProtKB:P09368	8 others
proline catabolic process	ISS (PMID:17072883) with UniProtKB:P09368	none
Cellular Component
mitochondrial matrix	ISS (PMID:17072883) with UniProtKB:P09368	143 others
Molecular Function
proline dehydrogenase activity	ISS (PMID:17072883) with UniProtKB:P09368	none

Catalytic Activity

EC 1.5.99.8 : IUBMB

Published Expression Profiles

Gene Expression Viewer Cell Cycle

Gene Expression Viewer Meiosis

Gene Expression Viewer Environmental Stress

Gene Expression Viewer Pheromone Response/Mating

TranscriptomeViewer SPCC70.03c High-resolution view of transcripts in neighbourhood

Array Express SPCC70.03c Array Express Expression profiles

Cyclebase SPCC70.03c Cell Cycle Expression Datasets

Literature

Search for in PubMed

Protein Families and Domains

View Pfam domain structure for this gene product

View SCOP superfamily

DB	Accs	Description
Pfam	PF01619	Proline dehydrogenase	(0 Others)
InterPro	IPR002872	Proline dehydrogenase
InterPro	IPR015659	Proline oxidase

Database Cross-References

DB	Accs	Description
UniProtKB	O74524	Probable proline oxidase, mitochondrial precursor (EC 1.5.99.8) (Proline dehydrogenase).
EMBL	CU329672	Schizosaccharomyces pombe chromosome III
BioGrid	SPCC70.03c	curated genetic and physical interactions
Ensembl	SPCC70.03c	Ensembl Fungi
NCBI Entrez Gene	SPCC70.03c	NCBI Entrez Gene
FYSSION	SPCC70.03c	FYSSION
NBRP	SPCC70.03c	Fission yeast strain database, National BioResource Project (Japan)
PIR	T41549	PIR
SPD	23/23H05	S. pombe Postgenome Database Orfeome Localization Data
YOGY	SPCC70.03c	Retrieval of eukaryotic orthologs

UniProtKB Annotation For This Protein

Catalytic Activity

L-proline + acceptor + H(2)O = (S)-1- pyrroline-5-carboxylate + reduced acceptor.

Cofactor

FAD.

Function

Converts proline to delta-1-pyrroline-5-carboxylate (By similarity).

Similarity

Belongs to the proline oxidase family.

Keywords

Complete proteome (4977 others) , Mitochondrion (328 others) , Oxidoreductase (184 others) , Proline metabolism (2 others) , Transit peptide (165 others)

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