CDS: SPCC11E10.01


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General Information

Systematic Name

SPCC11E10.01

Gene Synonyms

SPCC61.06

Status

role inferred from homology

Product

cystathionine beta-lyase (predicted)

Type

CDS

Sequence

DNA and Protein

Location

Chromosome

Contig Location

1453242..1454414 (Unspliced length: 1173 bp)

Exons

1453242..1454414 (Spliced length: 1173 bp)

Region download and display (in Artemis)

Genome Browser

Context Map:
Context Feature Map

spt3 SPCC61.03 SPCC61.04c SPCC61.05 >SPCC11E10.01< gpi8 mug1 SPCC11E10.04 ynd1 SPCC11E10.06c SPCC11E10.07c

Curation

Term	Other genes annotated to this term
orthologous to S. cerevisiae YGL184C	(0 Others)
conserved in Eukaryotes	(4113 Others)
conserved in Bacteria	(830 Others)
conserved in Metazoa	(3558 Others)
conserved in Vertebrates	(3556 Others)
conserved in Fungi	(4163 Others)
predominantly uniformly single copy (one to one)	(2867 Others)

Predicted Peptide Properties

Mass

42.7 kDa	Amino acids	390
pH 7.0	Charge	3.0

Isoelectric point

Signal Peptide

Not found

Transmembrane Domains

0 found

GPI Anchor

Not found

Gene Ontology Annotation

Term (browse Amigo)	Evidence	Other genes annotated to this term
Biological Process
L-methionine biosynthetic process from L-homoserine via cystathionine	IC (PMID:17072883) from GO:0004121	1 other
Cellular Component
peroxisome	ISS (PMID:17072883) with UniProtKB:P53101	23 others
Molecular Function
cystathionine beta-lyase activity	ISS (PMID:17072883) with UniProtKB:Q96VU8	none
pyridoxal phosphate binding	IEA (GO_REF:0000002) with InterPro:IPR015422	39 others

Catalytic Activity

EC 4.4.1.8 : IUBMB

Published Expression Profiles

Gene Expression Viewer Cell Cycle

Gene Expression Viewer Meiosis

Gene Expression Viewer Environmental Stress

Gene Expression Viewer Pheromone Response/Mating

TranscriptomeViewer SPCC11E10.01 High-resolution view of transcripts in neighbourhood

Array Express SPCC11E10.01 Array Express Expression profiles

Cyclebase SPCC11E10.01 Cell Cycle Expression Datasets

Literature

Search for in PubMed

Protein Families and Domains

View Pfam domain structure for this gene product

View SCOP superfamily

DB	Accs	Description
Pfam	PF01053	Cys/Met metabolism PLP-dependent enzyme	(3 Others)
InterPro	IPR000277	Cys/Met metabolism, pyridoxal phosphate-dependent enzyme
InterPro	IPR006238	Cystathionine beta-lyase, eukaryotic
InterPro	IPR015421	Pyridoxal phosphate-dependent transferase, major region, subdomain 1
InterPro	IPR015422	Pyridoxal phosphate-dependent transferase, major region, subdomain 2
PROSITE	PS00868	Cys/Met metabolism enzymes pyridoxal-phosphate attachment site.

Database Cross-References

DB	Accs	Description
UniProtKB	O94350	Cystathionine beta-lyase (Predicted) (EC 4.4.1.8).
EMBL	CU329672	Schizosaccharomyces pombe chromosome III
BioGrid	SPCC11E10.01	curated genetic and physical interactions
Ensembl	SPCC11E10.01	Ensembl Fungi
NCBI Entrez Gene	SPCC11E10.01	NCBI Entrez Gene
FYSSION	SPCC11E10.01	FYSSION
NBRP	SPCC11E10.01	Fission yeast strain database, National BioResource Project (Japan)
SPD	40/40D04	S. pombe Postgenome Database Orfeome Localization Data
YOGY	SPCC11E10.01	Retrieval of eukaryotic orthologs

UniProtKB Annotation For This Protein

Keywords

Complete proteome (4977 others) , Lyase (60 others)

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