|
| Name | sen1 |
| Systematic Name | SPAC6G9.10c |
| Status |
experimentally characterised (or published) |
| Product |
ATP-dependent 5' to 3' DNA/RNA helicase Sen1
|
| Type | CDS |
| Sequence | DNA and Protein |
|
| Chromosome | 1 |
| Contig Location | complement(3262462..3267525) (Unspliced length: 5064 bp) |
| Exons | complement(3262462..3267525) (Spliced length: 5064 bp) |
|
Region download and display (in Artemis)
|
Genome Browser
|
Context Map:
 mug79 pcd1 pcp1 arc4 ubp6 rpl24 >sen1< syb1 cfr1 bqt1 SPAC6G9.14 SPAC6G9.15c |
|
| Term |
Db xref/URL |
Qualifiers |
Other genes annotated to this term |
|---|
| phenotype, viable | PMID:20473289 | deletion | (3601 Others) | | DNA2/NAM7 family | | | (1 Other) | | DEAD/DEAH box helicase | | | (60 Others) | | orthologous to S. cerevisiae YLR430W | | | (1 Other) | | disease associated, Ataxia-ocular apraxia 2 | | | (0 Others) | | species distribution, conserved in Eukaryotes | | | (4429 Others) | | species distribution, conserved in Metazoa | | | (3603 Others) | | species distribution, conserved in Vertebrates | | | (3585 Others) | | species distribution, predominantly uniformly single copy (one to one) | | | (2885 Others) | | species distribution, conserved in Fungi | | | (4514 Others) | | species distribution, conserved in Eukaryotes only | | | (2489 Others) | | disease associated, neurological disorders | | | (30 Others) |
|
|
|
| Mass |
| 192.5 kDa |
Amino acids | 1687 |
| pH 7.0 |
Charge | 8.5 |
|
| Isoelectric point |
 |
| Signal Peptide | Not found |
| Transmembrane Domains | 0 found |
| GPI Anchor | Not found |
|
|
|
|
| Gene Expression Viewer Cell Cycle |
| Gene Expression Viewer Meiosis |
| Gene Expression Viewer Environmental Stress |
| Gene Expression Viewer Pheromone Response/Mating |
| TranscriptomeViewer SPAC6G9.10c High-resolution view of transcripts in neighbourhood
|
| Array Express SPAC6G9.10c Array Express Expression profiles
|
| Cyclebase SPAC6G9.10c Cell Cycle Expression Datasets
|
|
| Search for sen1 in PubMed |
|
| View Pfam domain structure for this gene product |
| View SCOP superfamily |
|
| DB |
Accs |
Description |
| UniProtKB | Q92355 | Helicase sen1 (EC 3.6.1.-) (Endonuclease sen1). |
| EMBL | CU329670 | Schizosaccharomyces pombe chromosome I |
| BioGrid | SPAC6G9.10c | curated genetic and physical interactions |
| Ensembl | SPAC6G9.10c | Ensembl Fungi |
| NCBI Entrez Gene | SPAC6G9.10c | NCBI Entrez Gene |
| FYSSION | SPAC6G9.10c | FYSSION |
| NBRP | SPAC6G9.10c | Fission yeast strain database, National BioResource Project (Japan) |
| PIR | T39072 | PIR |
| SPD | 31/31B03 | S. pombe Postgenome Database Orfeome Localization Data |
| UCSC_Browser | SPAC6G9.10c | UCSC_Browser |
| YOGY | SPAC6G9.10c | Retrieval of eukaryotic orthologs |
|
|
| Function | Binds to DNA and RNA and has a 5'->3' endonuclease activity. Has a role in tRNA, mRNA, and snoRNA splicing. |
| Similarity | Belongs to the DNA2/NAM7 helicase family. |
| Subcellular Location | Nucleus (Potential). |
| Subunit | Monomer. |
| Keywords |
ATP-binding
(407 others)
,
Complete proteome
(4976 others)
,
Direct protein sequencing
(87 others)
,
Helicase
(80 others)
,
Hydrolase
(451 others)
,
mRNA processing
(103 others)
,
mRNA splicing
(76 others)
,
Nuclease
(43 others)
,
Nucleotide-binding
(481 others)
,
Nucleus
(1205 others)
,
tRNA processing
(37 others)
|
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