|
| Name | hem1 |
| Systematic Name | SPAC2F3.09 |
| Reserved Name | hem1 |
| Status |
role inferred from homology |
| Product |
5-aminolevulinate synthase
|
| Type | CDS |
| Sequence | DNA and Protein |
|
| Chromosome | 1 |
| Contig Location | 3940263..3941939 (Unspliced length: 1677 bp) |
| Exons | 3940263..3941939 (Spliced length: 1677 bp) |
|
Region download and display (in Artemis)
|
Genome Browser
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Context Map:
 SPAC2F3.05c kap104 SPAC2F3.07c sut1 >hem1< SPAC2F3.18c SPAC2F3.10 SPAC2F3.11 SPAC2F3.12c SPAC2F3.13c saf2 SPNCRNA.239 |
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| Mass |
| 60.9 kDa |
Amino acids | 558 |
| pH 9.2 |
Charge | 24.5 |
|
| Isoelectric point |
 |
| Signal Peptide | Not found |
| Transmembrane Domains | 0 found |
| GPI Anchor | Not found |
|
|
|
| EC 2.3.1.37 :
IUBMB
|
|
| Gene Expression Viewer Cell Cycle |
| Gene Expression Viewer Meiosis |
| Gene Expression Viewer Environmental Stress |
| Gene Expression Viewer Pheromone Response/Mating |
| TranscriptomeViewer SPAC2F3.09 High-resolution view of transcripts in neighbourhood
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| Array Express SPAC2F3.09 Array Express Expression profiles
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| Cyclebase SPAC2F3.09 Cell Cycle Expression Datasets
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| Search for hem1 in PubMed |
|
| View Pfam domain structure for this gene product |
| View SCOP superfamily |
| DB |
Accs |
Description |
|
| Pfam | PF00155 | Aminotransferase class I and II |
(10 Others) |
| InterPro | IPR010961 | Tetrapyrrole biosynthesis, 5-aminolevulinic acid synthase |
|
| InterPro | IPR004839 | Aminotransferase, class I and II |
|
| InterPro | IPR001917 | Aminotransferase, class-II, pyridoxal-phosphate binding site |
|
| InterPro | IPR015421 | Pyridoxal phosphate-dependent transferase, major region, subdomain 1 |
|
| PROSITE | PS00599 | Aminotransferases class-II pyridoxal-phosphate attachment site. |
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| DB |
Accs |
Description |
| UniProtKB | O14092 | 5-aminolevulinate synthase, mitochondrial precursor (EC 2.3.1.37) (5- aminolevulinic acid synthase) (Delta-aminolevulinate synthase) (Delta- ALA synthetase). |
| EMBL | CU329670 | Schizosaccharomyces pombe chromosome I |
| BioGrid | SPAC2F3.09 | curated genetic and physical interactions |
| Ensembl | SPAC2F3.09 | Ensembl Fungi |
| NCBI Entrez Gene | SPAC2F3.09 | NCBI Entrez Gene |
| FYSSION | SPAC2F3.09 | FYSSION |
| NBRP | SPAC2F3.09 | Fission yeast strain database, National BioResource Project (Japan) |
| PIR | T38542 | PIR |
| YOGY | SPAC2F3.09 | Retrieval of eukaryotic orthologs |
|
|
| Catalytic Activity | Succinyl-CoA + glycine = 5-aminolevulinate + CoA + CO(2). |
| Cofactor | Pyridoxal phosphate (By similarity). |
| Pathway | Porphyrin metabolism; protoporphyrin-IX biosynthesis; 5- aminolevulinate from glycine: step 1/1. |
| Similarity | Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. |
| Subcellular Location | Mitochondrion matrix (By similarity). |
| Keywords |
Acyltransferase
(52 others)
,
Complete proteome
(4977 others)
,
Heme biosynthesis
(7 others)
,
Mitochondrion
(328 others)
,
Pyridoxal phosphate
(39 others)
,
Transferase
(528 others)
,
Transit peptide
(165 others)
|
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