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CDS: SPAC19A8.14

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General Information   Add to Gene Basket  View Gene Basket
Systematic NameSPAC19A8.14     (Warning: This cosmid was reversed from its original orientation)
Status role inferred from homology
Product aminoacyl-tRNA hydrolase (predicted)    
TypeCDS
Sequence DNA and Protein
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Location
Chromosome 1
Contig Location complement(2460340..2460957)   (Unspliced length: 618 bp)
Exons complement(2460340..2460957)   (Spliced length: 618 bp)
Region download and display (in Artemis) Genome Browser
Context Map:
Context Feature Map

SPAC32A11.02c  phx1  trp2  >SPAC19A8.14<  usp101  dcp2  SPAC19A8.11c  rfp1  SPAC19A8.09  upf2  
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Curation
Term Db xref/URL Other genes annotated to this term
orthologous to S. cerevisiae YBL057C (0 Others)
conserved in Eukaryotes (4113 Others)
conserved in Bacteria (830 Others)
conserved in Metazoa (3558 Others)
conserved in Vertebrates (3556 Others)
conserved in Fungi (4163 Others)
predominantly uniformly single copy (one to one) (2867 Others)
modification, phosphorylatedPMID:18257517(695 Others)
 
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Predicted Peptide Properties
Mass
21.4 kDa Amino acids 205
pH 5.8 Charge -1.0
Isoelectric point
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Signal PeptideSignal peptide predicted for SPAC19A8.14 by SignalP 2.0 HMM (Signal peptide probability 0.791, signal anchor probability 0.138) with cleavage site probability 0.633 between residues 24 and 25
Transmembrane Domains1 probable transmembrane helix predicted for SPAC19A8.14 by TMHMM2.0 at aa 5-27
GPI AnchorGPI-Anchor Signal predicted for SPAC19A8.14 by DGPI v2.04 with cleavage site probability 1.044 near 181
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Gene Ontology Annotation
Term (browse Amigo) Qualifier Evidence Other genes annotated to this term
Biological Process
mitochondrial translation  RCA (PMID:17072883) with GOC:pombekw2GO 122 others
translation  ISS (PMID:17072883) with UniProtKB:P34222 629 others
Cellular Component
cytoplasm  ISS (PMID:17072883) with UniProtKB:P34222 4239 others
mitochondrion  ISS (PMID:17072883) with UniProtKB:P34222 722 others
mitochondrion  IDA (PMID:16823372) 722 others
Molecular Function
aminoacyl-tRNA hydrolase activity  ISS (PMID:17072883) with UniProtKB:P34222 2 others
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Catalytic Activity
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Published Expression Profiles
Gene Expression Viewer Cell Cycle
Gene Expression Viewer Meiosis
Gene Expression Viewer Environmental Stress
Gene Expression Viewer Pheromone Response/Mating
TranscriptomeViewer      SPAC19A8.14 High-resolution view of transcripts in neighbourhood
Array Express                   SPAC19A8.14 Array Express Expression profiles
Cyclebase                          SPAC19A8.14 Cell Cycle Expression Datasets
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Literature
Search for in PubMed
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Protein Families and Domains
View Pfam domain structure for this gene product
View SCOP superfamily
DB Accs Description
PfamPF01981Peptidyl-tRNA hydrolase PTH2 (0 Others)
InterProIPR002833Peptidyl-tRNA hydrolase, PTH2
ProDomPD010667ProDom
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Database Cross-References
DB Accs Description
UniProtKBO13830Probable peptidyl-tRNA hydrolase 2 (EC 3.1.1.29) (PTH 2).
EMBLCU329670Schizosaccharomyces pombe chromosome I
BioGridSPAC19A8.14curated genetic and physical interactions
EnsemblSPAC19A8.14Ensembl Fungi
NCBI Entrez GeneSPAC19A8.14NCBI Entrez Gene
FYSSIONSPAC19A8.14FYSSION
NBRPSPAC19A8.14Fission yeast strain database, National BioResource Project (Japan)
PIRT37947PIR
YOGYSPAC19A8.14Retrieval of eukaryotic orthologs
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UniProtKB Annotation For This Protein
Catalytic ActivityN-substituted aminoacyl-tRNA + H(2)O = N- substituted amino acid + tRNA.
Function The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity).
SimilarityBelongs to the PTH2 family.
Keywords Complete proteome  (4977 others) ,   Hydrolase  (451 others)
 
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